Product Description
Palbociclib is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6, thus blocking cancer growth. CDK 4 and CDK 6 are proteins found both in healthy cells and cancer cells that stimulate cells to grow and divide. In breast cancer, these proteins can become overactive and cause the cells to grow and divide uncontrollably. Palbociclib prevents cellular transcription by blocking advancement from G1 to the S phase during cell cycle division, thus slowing or stopping the growth of breast cancer.